Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization

Piwi proteins such as Drosophila Aubergine (Aub) and mouse Miwi are essential for germline development and for primordial germ cell (PGC) specification. They bind piRNAs and contain symmetrically dimethylated arginines (sDMAs), catalyzed by dPRMT5. PGC specification in Drosophila requires maternal i...

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Detalhes bibliográficos
Main Authors: Kirino, Yohei, Vourekas, Anastassios, Sayed, Nabil, de Lima Alves, Flavia, Thomson, Travis, Lasko, Paul, Rappsilber, Juri, Jongens, Thomas A., Mourelatos, Zissimos
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802038/
https://ncbi.nlm.nih.gov/pubmed/19926723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1869710
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