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CD28(−) T cells: their role in the age-associated decline of immune function
The accumulation of CD28(−) T cells, particularly within the CD8 subset, is one of the most prominent changes during T cell homeostasis and function associated with aging in human. CD28, a major co-stimulatory receptor, is responsible for the optimal antigen-mediated T cell activation, proliferation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801888/ https://ncbi.nlm.nih.gov/pubmed/19540809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2009.03.013 |
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