Cardiac Resynchronization Therapy Corrects Dyssynchrony-induced Regional Gene Expression Changes on a Genomic Level

BACKGROUND: Cardiac electromechanical dyssynchrony causes regional disparities in workload, oxygen consumption, and myocardial perfusion within the left ventricle. We hypothesized that such dyssynchrony also induces region-specific alterations in the myocardial transcriptome that are corrected by ca...

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Autori principali: Barth, Andreas S, Aiba, Takeshi, Halperin, Victoria, DiSilvestre, Deborah, Chakir, Khalid, Colantuoni, Carlo, Tunin, Richard S, Dimaano, V Lea, Yu, Wayne, Abraham, Theodore P, Kass, David A, Tomaselli, Gordon F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801868/
https://ncbi.nlm.nih.gov/pubmed/20031609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.108.832345
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