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A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women

Female sex is an independent risk factor for development of torsade de pointes (TdP)-type arrhythmias in both congenital and acquired long QT syndrome (LQTS). In females, QT(c) interval and TdP risk vary during the menstrual cycle and around delivery. Biological experiments including single-cell cur...

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Detalhes bibliográficos
Main Authors: Furukawa, Tetsushi, Kurokawa, Junko, Clancy, Colleen E
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801855/
https://ncbi.nlm.nih.gov/pubmed/20066131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157340308786349507
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