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Apoptosis Induction and Growth Suppression by U19/Eaf2 Is Mediated Through its ELL-Binding Domain
BACKGROUND: U19/Eaf2 is an androgen-response gene and its downregulation is frequently observed in advanced human prostate cancer. U19/Eaf2 interacts with ELL, a fusion partner of MLL in the (11;19) (q23;p13.1) translocation in acute myeloid leukemia. U19/Eaf2 overexpression induces apoptosis and su...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801832/ https://ncbi.nlm.nih.gov/pubmed/17044034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20481 |
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