Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease.

Several lines of evidence indicate that tachykinin neuropeptides [substance P (SP), substance K (SK), and neuromedin K (NK)] play a role in regulating the inflammatory and immune responses. To test this hypothesis in a human inflammatory disease, quantitative receptor autoradiography was used to exa...

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Detalhes bibliográficos
Main Authors: Mantyh, C R, Gates, T S, Zimmerman, R P, Welton, M L, Passaro, E P, Vigna, S R, Maggio, J E, Kruger, L, Mantyh, P W
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280179/
https://ncbi.nlm.nih.gov/pubmed/2834738
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