Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease.

Several lines of evidence indicate that tachykinin neuropeptides [substance P (SP), substance K (SK), and neuromedin K (NK)] play a role in regulating the inflammatory and immune responses. To test this hypothesis in a human inflammatory disease, quantitative receptor autoradiography was used to exa...

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Hlavní autoři: Mantyh, C R, Gates, T S, Zimmerman, R P, Welton, M L, Passaro, E P, Vigna, S R, Maggio, J E, Kruger, L, Mantyh, P W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC280179/
https://ncbi.nlm.nih.gov/pubmed/2834738
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