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Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2

Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer and other human diseases. Fumagillin and ovalicin compose a class of structurally related natural products that potently inhibit angiogenesis by blocking endothelial cell proliferation. A synthetic analog o...

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Main Authors: Griffith, Eric C., Su, Zhuang, Niwayama, Satomi, Ramsay, Cameron A., Chang, Yie-Hwa, Liu, Jun O.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC28017/
https://ncbi.nlm.nih.gov/pubmed/9860943
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