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Rapid detection of SMARCB1 sequence variation using high resolution melting

BACKGROUND: Rhabdoid tumors are rare cancers of early childhood arising in the kidney, central nervous system and other organs. The majority are caused by somatic inactivating mutations or deletions affecting the tumor suppressor locus SMARCB1 [OMIM 601607]. Germ-line SMARCB1 inactivation has been r...

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Autori principali: Dagar, Vinod, Chow, Chung-Wo, Ashley, David M, Algar, Elizabeth M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801682/
https://ncbi.nlm.nih.gov/pubmed/20003390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-437
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