Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent

BACKGROUND: Autophagy has been shown recently to play an important role in the intracellular survival of several pathogenic bacteria. In this study, we investigated the effect of a novel small-molecule autophagy-inducing agent, AR-12, on the survival of Francisella tularensis, the causative bacteriu...

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Hlavní autoři: Chiu, Hao-Chieh, Soni, Shilpa, Kulp, Samuel K, Curry, Heather, Wang, Dasheng, Gunn, John S, Schlesinger, Larry S, Chen, Ching-Shih
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801672/
https://ncbi.nlm.nih.gov/pubmed/20003180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-110
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