The p38 MAPK Regulates IL-24 Expression by Stabilization of the 3′ UTR of IL-24 mRNA

BACKGROUND: IL-24 (melanoma differentiation-associated gene-7 (mda-7)), a member of the IL-10 cytokine family, possesses the properties of a classical cytokine as well as tumor suppressor effects. The exact role of IL-24 in the immune system has not been defined but studies have indicated a role for...

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Main Authors: Otkjaer, Kristian, Holtmann, Helmut, Kragstrup, Tue Wenzel, Paludan, Søren Riis, Johansen, Claus, Gaestel, Matthias, Kragballe, Knud, Iversen, Lars
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801610/
https://ncbi.nlm.nih.gov/pubmed/20072629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008671
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