The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.

IL-24 (melanoma differentiation-associated gene-7 (mda-7)), a member of the IL-10 cytokine family, possesses the properties of a classical cytokine as well as tumor suppressor effects. The exact role of IL-24 in the immune system has not been defined but studies have indicated a role for IL-24 in in...

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Bibliografske podrobnosti
Main Authors: Kristian Otkjaer, Helmut Holtmann, Tue Wenzel Kragstrup, Søren Riis Paludan, Claus Johansen, Matthias Gaestel, Knud Kragballe, Lars Iversen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2010-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC2801610?pdf=render
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