Natural Killer Cells in Obesity: Impaired Function and Increased Susceptibility to the Effects of Cigarette Smoke

BACKGROUND: Obese individuals who smoke have a 14 year reduction in life expectancy. Both obesity and smoking are independantly associated with increased risk of malignancy. Natural killer cells (NK) are critical mediators of anti-tumour immunity and are compromised in obese patients and smokers. We...

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Main Authors: O'Shea, Donal, Cawood, Tom J., O'Farrelly, Cliona, Lynch, Lydia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801590/
https://ncbi.nlm.nih.gov/pubmed/20107494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008660
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