Human thymic epithelial cells directly induce activation of autologous immature thymocytes.

To study the role that epithelial cells of the thymic microenvironment play in promoting activation of immature CD7+, CD2+, CD4-, CD8- (double-negative) human thymocytes, we have isolated thymocyte subsets from normal postnatal thymus and have cocultured autologous double-negative thymocytes with pu...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Denning, S M, Kurtzberg, J, Le, P T, Tuck, D T, Singer, K H, Haynes, B F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3129728/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.9.3125
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