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Activation of the ovine hypothalamic-pituitary-adrenal axis and febrile response by interleukin-6: A comparative study with bacterial lipopolysaccharide endotoxin
Sheep were subjected to immune challenge with either recombinant human interleukin-6 (rhIL-6; 2.0 μg/kg; n = 5), Escherichia coli lipopolysaccharide (LPS) endotoxin (400 ng/kg; n = 7), or saline (n = 6) to determine if IL-6 activates the febrile and hypothalamic-pituitary-adrenal axis (HPAA) respons...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Canadian Veterinary Medical Association
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801308/ https://ncbi.nlm.nih.gov/pubmed/20357955 |
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