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Activation of the ovine hypothalamic-pituitary-adrenal axis and febrile response by interleukin-6: A comparative study with bacterial lipopolysaccharide endotoxin

Sheep were subjected to immune challenge with either recombinant human interleukin-6 (rhIL-6; 2.0 μg/kg; n = 5), Escherichia coli lipopolysaccharide (LPS) endotoxin (400 ng/kg; n = 7), or saline (n = 6) to determine if IL-6 activates the febrile and hypothalamic-pituitary-adrenal axis (HPAA) respons...

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Bibliografske podrobnosti
Main Authors: Karrow, Niel A., You, Qiumei, McNicoll, Carl, Hay, Jack
Format: Artigo
Jezik:Inglês
Izdano: Canadian Veterinary Medical Association 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801308/
https://ncbi.nlm.nih.gov/pubmed/20357955
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