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Antigen Binding to Secretory Immunoglobulin A Results in Decreased Sensitivity to Intestinal Proteases and Increased Binding to Cellular Fc Receptors

In intestinal secretions, secretory IgA (SIgA) plays an important sentinel and protective role in the recognition and clearance of enteric pathogens. In addition to serving as a first line of defense, SIgA and SIgA·antigen immune complexes are selectively transported across Peyer's patches to u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duc, Mélanie, Johansen, Finn-Eirik, Corthésy, Blaise
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801296/
https://ncbi.nlm.nih.gov/pubmed/19910466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059220
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