Isolation of Novel Animal Cell Lines Defective in Glycerolipid Biosynthesis Reveals Mutations in Glucose-6-phosphate Isomerase

Glycerolipids are structural components for membranes and serve in energy storage. We describe here the use of a photodynamic selection technique to generate a population of Chinese hamster ovary cells that display a global deficiency in glycerolipid biosynthesis. One isolate from this population, G...

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Detalhes bibliográficos
Main Authors: Haller, Jorge F., Smith, Conor, Liu, Dailan, Zheng, Hongying, Tornheim, Keith, Han, Gil-Soo, Carman, George M., Zoeller, Raphael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801288/
https://ncbi.nlm.nih.gov/pubmed/19903819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068213
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