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Catalytic Mechanism of Bleomycin N-Acetyltransferase Proposed on the Basis of Its Crystal Structure

Bleomycin (Bm) N-acetyltransferase, BAT, is a self-resistance determinant in Bm-producing Streptomyces verticillus ATCC15003. In our present study, we crystallized BAT under both a terrestrial and a microgravity environment in the International Space Station. In addition to substrate-free BAT, the c...

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Detalhes bibliográficos
Main Authors: Oda, Kosuke, Matoba, Yasuyuki, Noda, Masafumi, Kumagai, Takanori, Sugiyama, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801270/
https://ncbi.nlm.nih.gov/pubmed/19889644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022277
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