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Crystallographic Study To Determine the Substrate Specificity of an l-Serine-Acetylating Enzyme Found in the d-Cycloserine Biosynthetic Pathway

DcsE, one of the enzymes found in the d-cycloserine biosynthetic pathway, displays a high sequence homology to l-homoserine O-acetyltransferase (HAT), but it prefers l-serine over l-homoserine as the substrate. To clarify the substrate specificity, in the present study we determined the crystal stru...

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Bibliografske podrobnosti
Main Authors: Oda, Kosuke, Matoba, Yasuyuki, Kumagai, Takanori, Noda, Masafumi, Sugiyama, Masanori
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624550/
https://ncbi.nlm.nih.gov/pubmed/23396912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02085-12
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