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Cannabinoid 1 Receptor and Interleukin-6 Receptor Together Induce Integration of Protein Kinase and Transcription Factor Signaling to Trigger Neurite Outgrowth

Activation of the G(o/i)-coupled cannabinoid 1 receptor (CB1R) has been shown to induce neurite outgrowth in Neuro2A cells through activation of Src kinase and STAT3 transcription factor. Signaling by the interleukin 6 receptor (IL-6R) also activates STAT3 through Jak kinase. We studied if signals f...

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Autors principals: Zorina, Yana, Iyengar, Ravi, Bromberg, Kenneth D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801262/
https://ncbi.nlm.nih.gov/pubmed/19861414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049841
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