Isoform-specific O-Glycosylation of Osteopontin and Bone Sialoprotein by Polypeptide N-Acetylgalactosaminyltransferase-1

Mucin-type O-glycan biosynthesis is regulated by the family of UDP-GalNAc polypeptide:N-acetylgalactosaminlytransfersases (ppGalNAcTs) that catalyzes the first step in the pathway by transferring GalNAc to Ser or Thr residues in a protein from the sugar donor UDP-GalNAc. Because not all Ser/Thr resi...

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Bibliographische Detailangaben
Hauptverfasser: Miwa, Hazuki E., Gerken, Thomas A., Jamison, Oliver, Tabak, Lawrence A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801249/
https://ncbi.nlm.nih.gov/pubmed/19880513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035436
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