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Complement Factor H Binds at Two Independent Sites to C-reactive Protein in Acute Phase Concentrations
Factor H (FH) regulates the activation of C3b in the alternative complement pathway, both in serum and at host cell surfaces. It is composed of 20 short complement regulator (SCR) domains. The Y402H polymorphism in FH is a risk factor for age-related macular degeneration. C-reactive protein (CRP) is...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801232/ https://ncbi.nlm.nih.gov/pubmed/19850925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.044529 |
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