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Complement Factor H Binds at Two Independent Sites to C-reactive Protein in Acute Phase Concentrations

Factor H (FH) regulates the activation of C3b in the alternative complement pathway, both in serum and at host cell surfaces. It is composed of 20 short complement regulator (SCR) domains. The Y402H polymorphism in FH is a risk factor for age-related macular degeneration. C-reactive protein (CRP) is...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Okemefuna, Azubuike I., Nan, Ruodan, Miller, Ami, Gor, Jayesh, Perkins, Stephen J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801232/
https://ncbi.nlm.nih.gov/pubmed/19850925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.044529
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