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Three-dimensional Model of Human Platelet Integrin αIIbβ3 in Solution Obtained by Small Angle Neutron Scattering

Integrin αIIbβ3 is the major membrane protein and adhesion receptor at the surface of blood platelets, which after activation plays a key role in platelet plug formation in hemostasis and thrombosis. Small angle neutron scattering (SANS) and shape reconstruction algorithms allowed formation of a low...

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Autores principales: Nogales, Aurora, García, Carolina, Pérez, Javier, Callow, Phil, Ezquerra, Tiberio A., González-Rodríguez, José
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801229/
https://ncbi.nlm.nih.gov/pubmed/19897481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050039
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