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Three-dimensional Model of Human Platelet Integrin αIIbβ3 in Solution Obtained by Small Angle Neutron Scattering

Integrin αIIbβ3 is the major membrane protein and adhesion receptor at the surface of blood platelets, which after activation plays a key role in platelet plug formation in hemostasis and thrombosis. Small angle neutron scattering (SANS) and shape reconstruction algorithms allowed formation of a low...

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Hlavní autoři: Nogales, Aurora, García, Carolina, Pérez, Javier, Callow, Phil, Ezquerra, Tiberio A., González-Rodríguez, José
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801229/
https://ncbi.nlm.nih.gov/pubmed/19897481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050039
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