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Rhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors

The role of rhodopsin as a structural prototype for the study of the whole superfamily of G protein-coupled receptors (GPCRs) is reviewed in an historical perspective. Discovered at the end of the nineteenth century, fully sequenced since the early 1980s, and with direct three-dimensional informatio...

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Bibliographic Details
Main Authors: Costanzi, Stefano, Siegel, Jeffrey, Tikhonova, Irina G., Jacobson, Kenneth A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801150/
https://ncbi.nlm.nih.gov/pubmed/20028316
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