The drusen-like phenotype in aging Ccl2 knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages

PURPOSE: Drusen, which can be defined clinically as yellowish white spots in the outer retina, are cardinal features of age-related macular degeneration (AMD). Ccl2 knockout (Ccl2(-/-)) mice have been reported to develop drusen and phenotypic features similar to AMD including an increased susceptibi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Luhmann, Ulrich F.O., Robbie, Scott, Munro, Peter M.G., Barker, Susie E., Duran, Yanai, Luong, Vy, Fitzke, Frederick W., Bainbridge, James W.B., Ali, Robin R., MacLaren, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801148/
https://ncbi.nlm.nih.gov/pubmed/19578022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3462
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker