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Fluorescence and UV resonance Raman study of peptide-vesicle interactions of human cathelicidin LL-37 and its F6W and F17W mutants

LL-37 is a broad-spectrum human antimicrobial peptide in the cathelicidin family. Potency assays in the form of minimal inhibitory concentration and vesicle leakage indicate that the single-tryptophan mutants, F6W and F17W, are as effective at killing bacteria and disrupting membranes as the native,...

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Detalhes bibliográficos
Main Authors: Gable, Jonathan E., Schlamadinger, Diana E., Cogen, Anna L., Gallo, Richard L., Kim, Judy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801029/
https://ncbi.nlm.nih.gov/pubmed/19894716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900996q
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