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Loss of integrin α1β1 ameliorates Kras-induced lung cancer

The collagen IV binding receptor integrin α1β1 has been shown to regulate lung cancer due to its pro-angiogenic properties, however it is unclear whether this receptor also plays a direct role in promoting primary lung tumors. To investigate this possibility, integrin α1-null mice were crossed with...

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Bibliografiska uppgifter
Huvudupphovsmän: Macias-Perez, Ines, Borza, Corina, Chen, Xiwu, Yan, Xuexian, Ibanez, Raquel, Mernaugh, Glenda, Matrisian, Lynn M., Zent, Roy, Pozzi, Ambra
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801028/
https://ncbi.nlm.nih.gov/pubmed/18676835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1395
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