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5-Lipoxygenase DNA Methylation and mRNA Content in the Brain and Heart of Young and Old Mice
The expression of 5-lipoxygenase (5-LOX) is affected by aging and regulated by epigenetic mechanisms including DNA methylation. We used methylation-sensitive restriction endonucleases (AciI, BstUI, HpaII, and HinP1I) to assess 5-LOX DNA methylation in brain and heart tissue samples from young (2 mon...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Hindawi Publishing Corporation
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801004/ https://ncbi.nlm.nih.gov/pubmed/20052386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/209596 |
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