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5-LIPOXYGENASE AND EPIGENETIC DNA METHYLATION IN AGING CULTURES OF CEREBELLAR GRANULE CELLS

5-Lipoxygenase (5-LOX), an enzyme involved in the metabolism of arachidonic acid, participates in the modulation of the proliferation and differentiation of neural stem cells and cerebellar granule cell (CGC) precursors. Since epigenetic mechanisms including DNA methylation regulate 5-LOX expression...

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Détails bibliographiques
Auteurs principaux: Imbesi, Marta, Dzitoyeva, Svetlana, Ng, Louisa W., Manev, Hari
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783316/
https://ncbi.nlm.nih.gov/pubmed/19778587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.09.039
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