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5-LIPOXYGENASE AND EPIGENETIC DNA METHYLATION IN AGING CULTURES OF CEREBELLAR GRANULE CELLS

5-Lipoxygenase (5-LOX), an enzyme involved in the metabolism of arachidonic acid, participates in the modulation of the proliferation and differentiation of neural stem cells and cerebellar granule cell (CGC) precursors. Since epigenetic mechanisms including DNA methylation regulate 5-LOX expression...

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Detalhes bibliográficos
Main Authors: Imbesi, Marta, Dzitoyeva, Svetlana, Ng, Louisa W., Manev, Hari
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783316/
https://ncbi.nlm.nih.gov/pubmed/19778587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.09.039
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