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Role of Protein Interactions in Defining HIV-1 Viral Capsid Shape and Stability: A Coarse-Grained Analysis

Coarse-grained models of the HIV-1 CA dimer are constructed based on all-atom molecular dynamics simulations. Coarse-grained representations of the capsid shell, which is composed of ∼1500 copies of CA proteins, are constructed and their stability is examined. A key interaction between carboxyl and...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Krishna, Vinod, Ayton, Gary S., Voth, Gregory A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800964/
https://ncbi.nlm.nih.gov/pubmed/20085716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.049
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