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Role of Protein Interactions in Defining HIV-1 Viral Capsid Shape and Stability: A Coarse-Grained Analysis
Coarse-grained models of the HIV-1 CA dimer are constructed based on all-atom molecular dynamics simulations. Coarse-grained representations of the capsid shell, which is composed of ∼1500 copies of CA proteins, are constructed and their stability is examined. A key interaction between carboxyl and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800964/ https://ncbi.nlm.nih.gov/pubmed/20085716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.049 |
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