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IL-17 signaling independent central nervous system autoimmunity is negatively regulated by TGFβ

Recent studies have established an important role of Th17 in induction of autoimmune diseases. We have found that although IL-17 receptor A (IL-17RA) −/− mice were resistant to experimental autoimmune encephalomyelitis (EAE), a small number of them developed milder clinical signs of this autoimmune...

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Detalhes bibliográficos
Main Authors: Gonzalez-García, Ines, Zhao, Yani, Ju, Songguang, Gu, Qin, Liu, Lin, Kolls, Jay, Lu, Binfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800821/
https://ncbi.nlm.nih.gov/pubmed/19234160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802221
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