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IL-17 signaling independent central nervous system autoimmunity is negatively regulated by TGFβ

Recent studies have established an important role of Th17 in induction of autoimmune diseases. We have found that although IL-17 receptor A (IL-17RA) −/− mice were resistant to experimental autoimmune encephalomyelitis (EAE), a small number of them developed milder clinical signs of this autoimmune...

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Autors principals: Gonzalez-García, Ines, Zhao, Yani, Ju, Songguang, Gu, Qin, Liu, Lin, Kolls, Jay, Lu, Binfeng
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800821/
https://ncbi.nlm.nih.gov/pubmed/19234160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802221
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