Chromosomal organization of the cytochrome P450-2C gene family in the mouse: a locus associated with constitutive aryl hydrocarbon hydroxylase.

Cytochromes P-450 represent a superfamily of enzymes with a central role in the metabolism of drugs, chemical toxins, and carcinogens. We have used genetic analysis to establish the complexity and catalytic function of a recently identified constitutively expressed murine hepatic cytochrome P-450 en...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Meehan, R R, Speed, R M, Gosden, J R, Rout, D, Hutton, J J, Taylor, B A, Hilkens, J, Kroezen, V, Hilgers, J, Adesnik, M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280058/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2895926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2662
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