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Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis

Motivation: The molecular complexity of a tumor manifests itself at the genomic, epigenomic, transcriptomic and proteomic levels. Genomic profiling at these multiple levels should allow an integrated characterization of tumor etiology. However, there is a shortage of effective statistical and bioinf...

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Autors principals: Shen, Ronglai, Olshen, Adam B., Ladanyi, Marc
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800366/
https://ncbi.nlm.nih.gov/pubmed/19759197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp543
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