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Pan-cancer identification of clinically relevant genomic subtypes using outcome-weighted integrative clustering

BACKGROUND: Comprehensive molecular profiling has revealed somatic variations in cancer at genomic, epigenomic, transcriptomic, and proteomic levels. The accumulating data has shown clearly that molecular phenotypes of cancer are complex and influenced by a multitude of factors. Conventional unsuper...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Arora, Arshi, Olshen, Adam B., Seshan, Venkatraman E., Shen, Ronglai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716509/
https://ncbi.nlm.nih.gov/pubmed/33272320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00804-8
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