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cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment.

cDNA clones encoding human topoisomerase I were isolated from an expression vector library (lambda gt11) screened with autoimmune anti-topoisomerase I serum. One of these clones has been expressed as a fusion protein comprised of a 32-kDa fragment of the bacterial TrpE protein linked to 67.7 kDa of...

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Detalhes bibliográficos
Main Authors: D'Arpa, P, Machlin, P S, Ratrie, H, Rothfield, N F, Cleveland, D W, Earnshaw, W C
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280033/
https://ncbi.nlm.nih.gov/pubmed/2833744
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