Binding of antiestrogens exposes an occult antigenic determinant in the human estrogen receptor.

Treatment of human breast cancer cytosol with tamoxifen (Tam) or 4-monohydroxytamoxifen (MHT) enhances the immunoreactivity of the estrogen receptor toward monoclonal antibody H222 but not monoclonal antibodies D547 or D75. This effect is evident from an increase in the apparent receptor content mea...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Martin, P M, Berthois, Y, Jensen, E V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1988
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280031/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2451827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.8.2533
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