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N-methylation: potential mechanism for metabolic activation of carcinogenic primary arylamines.

Two amine N-methyltransferases isolated from rabbit liver catalyze S-adenosylmethionine-dependent N-methylation of benzidine and 4-aminobiphenyl but not of 4-aminoazobenzene or 2-aminobiphenyl. The enzymatic reaction products were analyzed and found to be identical to synthetic N-methylbenzidine and...

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Bibliografske podrobnosti
Main Authors: Ziegler, D M, Ansher, S S, Nagata, T, Kadlubar, F F, Jakoby, W B
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC280027/
https://ncbi.nlm.nih.gov/pubmed/3357879
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