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The metabolic N-oxidation of carcinogenic arylamines in relation to nitrogen charge density and oxidation potential.

The N-oxidation of carcinogenic arylamines to form N-hydroxy arylamines has long been regarded as a necessary metabolic step for conversion to proximate carcinogenic derivatives. In contrast, arylamine ring-oxidation has been generally considered to be an important detoxification mechanism. Both enz...

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Main Authors: Kadlubar, F F, Fu, P P, Jung, H, Shaikh, A U, Beland, F A
格式: Artigo
語言:Inglês
出版: 1990
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567845/
https://ncbi.nlm.nih.gov/pubmed/2269230
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