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Identifying differentially methylated genes using mixed effect and generalized least square models

BACKGROUND: DNA methylation plays an important role in the process of tumorigenesis. Identifying differentially methylated genes or CpG islands (CGIs) associated with genes between two tumor subtypes is thus an important biological question. The methylation status of all CGIs in the whole genome can...

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Autors principals: Sun, Shuying, Yan, Pearlly S, Huang, Tim HM, Lin, Shili
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800121/
https://ncbi.nlm.nih.gov/pubmed/20003206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-404
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