HMG-CoA Reductase Inhibitor Improves Endothelial Dysfunction in Spontaneous Hypertensive Rats Via Down-regulation of Caveolin-1 and Activation of Endothelial Nitric Oxide Synthase

Hypertension is associated with endothelial dysfunction and increased cardiovascular risk. Caveolin-1 regulates nitric oxide (NO) signaling by modulating endothelial nitric oxide synthase (eNOS). The purpose of this study was to examine whether HMG-CoA reductase inhibitor improves impaired endotheli...

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Detalhes bibliográficos
Main Authors: Suh, Jung-Won, Choi, Dong-Ju, Chang, Hyuk-Jae, Cho, Young-Seok, Youn, Tae-Jin, Chae, In-Ho, Kim, Kwang-Il, Kim, Cheol-Ho, Kim, Hyo-soo, Oh, Buyng-Hee, Park, Young-Bae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800001/
https://ncbi.nlm.nih.gov/pubmed/20052342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2010.25.1.16
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