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Effect of Sildenafil on Neuropathic Pain and Hemodynamics in Rats
PURPOSE: The inhibition of phosphodiesterase 5 produces an antinociception through the increase of cyclic guanosine monophosphate (cGMP), and increasing cGMP levels enhance the release of γ-aminobutyric acid (GABA). Furthermore, this phosphodiesterase 5 plays a pivotal role in the regulation of the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Yonsei University College of Medicine
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799976/ https://ncbi.nlm.nih.gov/pubmed/20046518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2010.51.1.82 |
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