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Mutation patterns in cancer genomes

Recent large-scale cancer sequencing studies have focused primarily on identifying cancer-associated genes, but as an important byproduct provide “passenger mutation” data that can potentially illuminate the mutational mechanisms at work in cancer cells. Here, we explore patterns of nucleotide subst...

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Autors principals: Rubin, Alan F., Green, Phil
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799788/
https://ncbi.nlm.nih.gov/pubmed/19995982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912499106
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