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Mutational patterns in the breast cancer mitochondrial genome, with clinical correlates

The presence of mitochondrial DNA (mtDNA) mutations in human cancer has long been recognized, but their functional significance has remained obscure. Debate persists as to whether the mutations help drive the tumor, or are bystander events. Here, we analyze next-generation mtDNA sequence data from 9...

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Detalhes bibliográficos
Main Authors: McMahon, Sarah, LaFramboise, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004206/
https://ncbi.nlm.nih.gov/pubmed/24442641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu012
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