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Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors

In a life span study, we examined how the social environment regulates naturally occurring tumor development and malignancy in genetically prone Sprague–Dawley rats. We randomly assigned this gregarious species to live either alone or in groups of five female rats. Mammary tumor burden among social...

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Detalhes bibliográficos
Main Authors: Hermes, Gretchen L., Delgado, Bertha, Tretiakova, Maria, Cavigelli, Sonia A., Krausz, Thomas, Conzen, Suzanne D., McClintock, Martha K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799783/
https://ncbi.nlm.nih.gov/pubmed/20018726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910753106
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