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Relative Bioavailability of Chlorothiazide from Mucoadhesive Compacts in Pigs

The relative bioavailability of chlorothiazide from mucoadhesive polymeric compacts is compared to commercial oral suspension in pigs. A single-dose randomized study was conducted in 12 healthy pigs that are 9–10 weeks old. After overnight fasting, pigs were divided into two groups of six animals. T...

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Bibliografiske detaljer
Main Authors: Neelam, Karunakar, Mahalingam, Ravichandran, Birudaraj, Raj, Alfredson, Tom, Anne, Pratap, Li, Xiaoling, Jasti, Bhaskara R.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799598/
https://ncbi.nlm.nih.gov/pubmed/19902362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9332-0
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